Episode 56 - The Science of Longevity: Cellular Secrets with Greg Macpherson

Host Vicki Nguyen introduces One Body, One Life, a longevity-focused show sponsored by Jomies Fine Foods, and interviews Greg Macpherson, a New Zealand pharmacist and founder of SRW Laboratories.

Greg shares how working with residential care patients and discovering “The Hallmarks of Aging” shaped his focus on healthspan versus lifespan, using a Mount Everest analogy and noting healthspan is typically about 10 years shorter than lifespan.

He highlights key drivers of aging including DNA damage (with lifestyle strategies like “sunscreen for your cells”), personal viral burden and immune fatigue (including attention to absolute lymphocyte count), mitochondrial decline and targeted antioxidants like mitoquinol, and chronic inflammation linked to oxidative stress.

They discuss cellular senescence, fasting, time-restricted eating, exercise, and compounds like fisetin and quercetin, plus emerging areas like stem cells, peptides, biological age testing via DNA methylation, and future cellular “reprogramming,” along with Greg’s top lifestyle practices and where to find him (srw.co).